James Lyons-Weiler has taught genetics, ecology, bioinformatics, and evolution at institutions of higher learning in the United Stated. As a Sloan Postdoctoral Fellow he studied Molecular Evolutionary Genetics, and founded the Bioinformatics Analysis Core at the University of Pittsburgh and the Ebola Rapid Assay Development Consortium. A lifelong student of how methods in biological and medical research impose limits on understanding, he brings a vast and varied background to the problem of understanding all aspects of any topic he studies. He brings light to issues with a literary craft that helps the reader understand the issues, and the issues behind the issues, with clarity. In an era of big data and big money interests, he has paved new inroads into maintaining a classic focus on the scientific aspects of research.